Journal: Journal of Oncology
Article Title: Plumbagin Enhances the Anticancer Effects of PF Chemotherapy via Downregulation of the PI3K/AKT/mTOR/p70S6K Pathway in Human Tongue Squamous Cell Carcinoma
doi: 10.1155/2023/8306514
Figure Lengend Snippet: Viability of TSCC cells after various treatments. (a-c) Inhibition of the proliferation of Cal27 and Cal27/CDDP cells following treatment with PB, 5-Fu, and CDDP. (d) A combination of PB and PF exerted synergistic cytotoxic effects in Cal27 and Cal27/CDDP cells. TSCC, tongue squamous cell carcinoma; PB, plumbagin; 5-Fu, 5-fluorouracil; and PF, cisplatin plus 5-fluorouracil.
Article Snippet: The median inhibitory concentration (IC 50 ) was calculated with growth inhibition curves fitted to the data using GraphPad Prism 8.0.
Techniques: Inhibition